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The objective of the RPI-Bio team is to respond to the triple imperative of extreme and controlled gestures on living organisms (characterization, diagnosis, surgery, etc.). The team’s approach is global and multidisciplinary. It is based on a fundamental rapprochement between medical robotics, microrobotics, perception and AI. The team relies on a human perimeter associating roboticists, automaticians, computer scientists and practitioners (PU-PH and doctoral students-physicians).